Academy of Medical Sciences of I.R. Iran Archives of Iranian Medicine 1029-2977 21 4 2018 04 01 Nodular Hepatic Tuberculosis Masquerading as a Seminoma Liver Metastasis 180 182 EN Houssem Harbi Amine Chaabouni Rim Kallel Nozha Toumi Sami Fendri Jihene Krichene Salah Boujelbene Rafik Mzali Journal Article 2017 10 11 2018 01 17 Isolated macro-nodular liver tuberculosis is a very rare condition. It may mimic primitive or secondary tumors of the liver. This could delay or mislead the therapeutic management. An immunocompetent 48-year-old man with a history of non-metastatic seminoma was treated with right orchidectomy followed by 20 Gy radiotherapy. The discovery, 8 months later, of a 2 cm nodule of the hepatic dome evoked a liver metastasis. Percutaneous biopsy was not feasible. Wedge resection was performed whereas medical treatment would have sufficed, as pathologic examination of the resected specimen showed a macro-nodular hepatic tuberculosis. The patient received anti-tuberculosis drugs for 9 months. The diagnosis of isolated macro-nodular liver tuberculosis is frequently misleading, particularly in immunocompetent and paucisymptomatic patients. Thus percutaneous biopsy is mandatory for diagnosis and also prior to any major surgeries.