﻿<?xml version="1.0" encoding="UTF-8"?>
<ArticleSet>
  <Article>
    <Journal>
      <PublisherName>Academy of Medical Sciences of I.R. Iran</PublisherName>
      <JournalTitle>Archives of Iranian Medicine</JournalTitle>
      <Issn>1029-2977</Issn>
      <Volume>22</Volume>
      <Issue>3</Issue>
      <PubDate PubStatus="ppublish">
        <Year>2019</Year>
        <Month>04</Month>
        <DAY>01</DAY>
      </PubDate>
    </Journal>
    <ArticleTitle>Eosinophilic Granulomatosis with Polyangiitis in a 4-Year-Old Child: Is Montelukast and/or Clarithromycin a Trigger?</ArticleTitle>
    <FirstPage>161</FirstPage>
    <LastPage>163</LastPage>
    <Language>EN</Language>
    <AuthorList>
      <Author>
        <FirstName>Esma</FirstName>
        <LastName>Altinel Acoglu</LastName>
      </Author>
      <Author>
        <FirstName>Fatma</FirstName>
        <LastName>Yazilitas</LastName>
      </Author>
      <Author>
        <FirstName>Asuman</FirstName>
        <LastName>Gurkan</LastName>
      </Author>
      <Author>
        <FirstName>Eyup</FirstName>
        <LastName>Sari</LastName>
      </Author>
      <Author>
        <FirstName>Saliha</FirstName>
        <LastName>Senel</LastName>
      </Author>
      <Author>
        <FirstName>Meltem</FirstName>
        <LastName>Akcaboy</LastName>
      </Author>
    </AuthorList>
    <PublicationType>Journal Article</PublicationType>
    <ArticleIdList>
      <ArticleId IdType="doi">
      </ArticleId>
    </ArticleIdList>
    <History>
      <PubDate PubStatus="received">
        <Year>2018</Year>
        <Month>06</Month>
        <Day>01</Day>
      </PubDate>
      <PubDate PubStatus="accepted">
        <Year>2018</Year>
        <Month>12</Month>
        <Day>08</Day>
      </PubDate>
    </History>
    <Abstract>The aim of the presentation of this case is to discuss whether there is an association with eosinophilic granulomatosis with polyangiitis (EGPA) and the use of montelukast, and clarithromycin and to discuss a successful treatment course. A 4-year-old girl with a preceding history of asthma attacks and increased eosinophil counts was admitted. She had been using clarithromycin for five days and montelucast for a month. She was eventually diagnosed with EGPA with detailed examination. Clinicians should remember EGPA in children with asthma and hypereosinophilia. Patients receiving leukotriene receptor antagonists and/or macrolides should be monitored for developing a multisystem disease. Treatment with immunosuppressive agents may be required to ensure a good prognosis.</Abstract>
    <ObjectList>
      <Object Type="keyword">
        <Param Name="value">Children</Param>
      </Object>
      <Object Type="keyword">
        <Param Name="value">Churg strauss syndrome (CSS)</Param>
      </Object>
      <Object Type="keyword">
        <Param Name="value">Clarithromycin</Param>
      </Object>
      <Object Type="keyword">
        <Param Name="value">Eosinophilic granulomatosis with polyangiitis</Param>
      </Object>
      <Object Type="keyword">
        <Param Name="value">Montelukast</Param>
      </Object>
    </ObjectList>
  </Article>
</ArticleSet>