Academy of Medical Sciences of I.R. Iran Archives of Iranian Medicine 1029-2977 21 7 2018 07 01 Liver Transplantation Status in Iran: A Multi-center Report on the Main Transplant Indicators and Survival Rates 275 282 EN S. Ali Malek-Hosseini Ali Jafarian Saman Nikeghbalian Hossein Poustchi Kamran B. Lankarani Mohsen Nasiri Toosi Heshmatollah Salahi Mohsen Dehghani Ahad Eshraghian Maryam Sharafkhah Sareh Eghtesad Nazgol Motamed-Gorji Kourosh Kazemi Javad Salimi Majid Moini Alireza Shamsaeefar Maryam Moini Masoud Dehghani Mohammad B. Khosravi Atabak Najafi Hossein Sattari Bita Geramizadeh Mohammad Shafiee Mohammad N. Toutouni Behnam Sanei Seyed Mohammadreza Nejatollahi Alireza Taghavi Ali Bahador Mohsen Aliakbarian Bijan Eghtesad Reza Malekzadeh Journal Article 2017 04 29 2018 05 17 Background: Iran’s experience with liver transplantation (LT) began more than two decades ago. The purpose of this article is to present the status of LT in Iran, review specific characteristics of the programs, their outcomes, and their growth to become one of the largest LT programs in the world. Methods: A questionnaire, asking for data on the number of transplants performed and specifics of the recipients and type of donors with focus on indications and outcomes was sent to LT programs. Results: During a period of 23 years, 4,485 LTs were performed at 6 centers in the country. Of these, 4106 were from deceased donors and 379 were from living donors. There were 3553 adults and 932 pediatric recipients. Hepatitis B and biliary atresia were the most common etiologies in adult and pediatric patients, respectively. Overall survival rates at 1, 5, and 10 years were 85%, 77%, and 71% for adults and 76%, 67% and 56% for pediatric patients, respectively. Conclusion: Approval of the brain death law in Iran and coordinated efforts by the transplant centers to build comprehensive LT programs has resulted in the ability to procure more than 700 deceased donors per year with acceptable long-term survival.